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Table 1 List of proteins correlating significantly with age and the associated biological functions

From: Age-associated changes in human tear proteome

Uniprot Full name Symbol Ra pb Cell death Cellular movement Inflammatory/immune response Viral infection
P80188 Neutrophil gelatinase-associated lipocalin LCN2 0.36 0.011 x x x x
P05109 Protein S100-A8 S100A8 0.40 0.004 x x x x
P06702 Protein S100-A9 S100A9 0.36 0.013 x x x x
P60709 Actin, cytoplasmic 1 ACTB 0.31 0.036 x x x x
P02768 Serum albumin ALB 0.35 0.013 x x x x
P04083 Annexin A1 ANXA1 0.37 0.010 x x x x
P07737 Profilin-1 PFN1 0.32 0.036 x x x  
P06396 Gelsolin GSN 0.32 0.036 x x   
P02787 Serotransferrin TF 0.37 0.010 x   x  
P63261 Actin, cytoplasmic 2 ACTG1 0.31 0.037 x    
P22314 Ubiquitin-like modifier-activating enzyme 1 UBA1 − 0.32 0.036 x    
P59665 Neutrophil defensin 1 DEFA1 0.40 0.004   x x  
P49788 Retinoic acid receptor responder protein 1 RARRES1 0.30 0.046   x   
Q8NBJ4 Golgi membrane protein 1 GOLM1 − 0.31 0.036     x
Q13296 Mammaglobin-A SCGB2A2 0.34 0.023     
Q14002 Carcinoembryonic antigen-related cell adhesion molecule 7 CEACAM7 0.32 0.036     
  1. aPearson’s product-moment correlation coefficient
  2. bBenjamini-Hochberg-adjusted p-value
  3. Expression based on 1 peptide only
  4. Proteins ACTB and ACTG1 are isoforms of the same protein